{"product_id":"kpv-fj","title":"KPV fJ","description":"\u003cp\u003e\u003cspan\u003eKPV is the naturally occurring C-terminal tripeptide (Lysine-Proline-Valine) of alpha-melanocyte-stimulating hormone (α-MSH), corresponding to residues 11-13 of the parent tridecapeptide. Despite being only three amino acids, KPV retains specific biological signaling properties distinct from the full-length α-MSH molecule.Laboratory research has investigated KPV's modulation of nuclear factor kappa-B (NF-κB) signaling, independent of classical melanocortin receptor (MCR) binding. In-vitro studies in macrophage and epithelial cell models have examined its effects on NF-κB nuclear translocation, IκB-α degradation, and downstream inflammatory cytokine expression (IL-1β, IL-6, TNF-α, IL-8). Research has also explored its interaction with intracellular signaling cascades in intestinal epithelial cell models and its transepithelial transport characteristics.Molecular Weight: 342.43 g\/mol. Sequence: Lys-Pro-Val. Appearance: White lyophilized powder. Solubility: Freely soluble in water. Storage: -20°C, lyophilized, sealed and protected from light. Small peptide size allows for higher molar concentrations per mg.\u003c\/span\u003e\u003c\/p\u003e","brand":"True Peptides","offers":[{"title":"10mg","offer_id":50579921961030,"sku":null,"price":49.97,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0828\/6781\/4470\/files\/2026-10-07_161142_861.png?v=1791428772","url":"https:\/\/true-peptokes.shop\/products\/kpv-fj","provider":"True Peptides","version":"1.0","type":"link"}